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November 9, 2005

Neonatal Signs After In Utero Exposure to Selective Serotonin Reuptake Inhibitors—Reply

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(18):2299-2301. doi:10.1001/jama.294.18.2300-b

In Reply: We appreciate the distinction between the timing of the SSRI-associated neonatal behavioral syndrome and that of infantile colic made by Dr Kaye and Ms Weinstein. We made this analogy because of the commonality of signs that comprise the SSRI-associated neonatal behavioral syndrome and colic (irritability and crying). Our intention was to place the SSRI-associated neonatal behavioral syndrome in the context of other mild, non–life-threatening syndromes that are familiar to a general audience. The statement that pregnant women should not discontinue their SSRIs to prevent colic or blame themselves for causing colic is a very important contribution to this discussion.

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