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December 14, 2005

Routine vs Selective Invasive Strategies in Acute Coronary Syndromes

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(22):2844-2846. doi:10.1001/jama.294.22.2844-b

To the Editor: In their Review, Dr Mehta and colleagues1 performed a meta-analysis that compared a routine invasive strategy with a selective invasive strategy in patients with unstable angina and non-ST-segment elevation (NSTE) acute coronary syndromes (ACS). The authors examined and pooled the results of 7 trials involving more than 9000 patients. They concluded that a routine invasive approach was associated with a nonsignificant reduction in overall mortality, although there was a significant increase in mortality during the index hospitalization.

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