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December 14, 2005

Circadian Rhythms and Reperfusion in Patients With Acute ST-Segment Elevation Myocardial Infarction—Reply

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(22):2846-2847. doi:10.1001/jama.294.22.2847-a

In Reply: We agree with Dr Manfredini and colleagues that morning-night variation and circadian rhythms might influence outcomes for patients with myocardial infarction. Future investigations should examine these issues as well as whether the effectiveness of percutaneous coronary intervention shows a circadian variation.

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