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Comment & Response
December 10, 2014

Colorectal Cancer and the Effect of Flexible Sigmoidoscopy Screening

Author Affiliations
  • 1Yukon Kuskokwim Health Corporation, Bethel, Alaska
JAMA. 2014;312(22):2411. doi:10.1001/jama.2014.14692

To the Editor In the study of flexible sigmoidoscopy screening and colorectal cancer incidence and mortality by Dr Holme and colleagues,1 the authors reported adjusted analyses of results without reporting either the measured results or the implications of their adjustments. Based on the data available in the article, the relative risk for colorectal cancer mortality in the screening vs control groups is 0.82 (95% CI, 0.63-1.06) and the rate ratio is 0.80 (95% CI, 0.61-1.04); neither are statistically significant.

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