Author Affiliations: Division of Endocrinology, Diabetes, and Metabolism, Tufts-New England Medical Center (Dr Dansinger); and Lipid Metabolism Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (Dr Schaefer), Boston, Mass.
The article by Howard and colleagues1 in this issue of JAMA, which reports on the largest, most ambitious randomized dietary intervention trial conducted to date, has concluded that a low-fat diet program does not produce weight gain.1 Despite the impressive features of this landmark study, the findings on long-term weight change are somewhat underwhelming.
Dansinger ML, Schaefer EJ. Low-Fat Diets and Weight Change. JAMA. 2006;295(1):94–95. doi:10.1001/jama.295.1.94