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February 8, 2006

Critically Ill Patients and Acute Renal Failure—Reply

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2006;295(6):624-625. doi:10.1001/jama.295.6.624-c

In Reply: In response to Drs d’Avila and Poli de Figueiredo, although our inclusion criteria did allow patients between the ages of 12 and 18 years to be included, this only occurred with 8 patients (5 of whom died) and thus is unlikely to have had any impact on the results of our study. With regard to the hospital mortality for patients who did and did not receive RRT, we found that mortality was higher in those treated with RRT compared with those who were not treated with RRT (62.1% vs 55.7%; P = .02, Fisher exact test), although their median SAPS II scores were identical (48 for both groups; P = .84). In our study, cardiac surgery patients with ARF had a hospital mortality of 53.9%, suggesting that this group might have a somewhat better prognosis than other subgroups. However, there were no differences in this group after controlling for other variables.

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