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March 15, 2006

Tests for Atypical Squamous Cells of Undetermined Significance

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2006;295(11):1247-1248. doi:10.1001/jama.295.11.1247-a

To the Editor: In his Clinical Crossroads article regarding atypical squamous cells of undetermined significance (ASC-US), Dr Sawaya1 suggests that research provides insufficient information to determine whether liquid-based or conventional cervical cytology screening should be preferred. He refers to the US Preventive Services Task Force 2003 conclusion that the published literature is inadequate to conclude which method is better.2

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