Additional research from the National Heart, Lung, and Blood Institute–funded Women’s Health Initiative has shown that calcium plus vitamin D supplements in healthy postmenopausal women provide a modest benefit in preserving bone mass and preventing hip fractures, but compliance was important to show a substantial benefit. However, the supplement did not show evidence of preventing colorectal cancer (Jackson RD et al. N Engl J Med. 2006;354:669-683; Wactawski-Wende J et al. N Engl J Med. 2006;354:684-696).
Hampton T. Calcium and Vitamin D. JAMA. 2006;295(12):1364. doi:10.1001/jama.295.12.1364-b