A new evidence report by the Agency for Healthcare Research and Quality has assessed the effectiveness of different diagnostic methods for detecting adnexal masses, enlargements in the area of the ovaries and fallopian tubes that are sometimes signs of ovarian cancer (http://www.ahrq.gov/downloads/pub/evidence/pdf/adnexal/adnexal.pdf). All methods analyzed showed trade-offs between sensitivity and specificity, and it was unclear whether any could be used to maximize appropriate treatment and minimize unnecessary surgery.
Hampton T. Diagnosing Ovarian Cancer. JAMA. 2006;295(16):1889. doi:10.1001/jama.295.16.1889-a