Letters Section Editor: Robert M. Golub, MD, Senior Editor.
In Reply: Drs Mascitelli and Pezzetta suggest analysis and possible correction for the presence of chronic thyroid disease because of its previously noted association with erectile dysfunction. Thyroid function was not assessed in the Prostate Cancer Prevention Trial (PCPT), and we were not able to test this covariate. However, the inception cohort for the trial was generally healthy; as shown in Table 1 of our article, 77% of the participants had a good or excellent global health index.
Thompson IM, Tangen CM, Goodman PJ, Probstfield JL, Moinpour CM, Coltman CA. Erectile Dysfunction and Incidence of Cardiovascular Disease—Reply. JAMA. 2006;295(17):1998-2000. doi:10.1001/jama.295.17.2000-a