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The World in Medicine
May 17, 2006

Predicting Drug Response

JAMA. 2006;295(19):2240. doi:10.1001/jama.295.19.2240-c

Because patients have variable responses to drugs due to individual differences in genetic makeup and environmental factors such as intestinal flora and diet, being able to predict a person's response to a medication would be useful and sometimes lifesaving. Now, scientists from England, Sweden, France, and the United States report that studies in animals suggest that a urine test might help physicians to fine-tune drug prescribing by showing how well an individual's body metabolizes the compound (Clayton TA et al. Nature. 2006;440:1073-1077).

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