Medical News and Perspectives
May 24/31, 2006

Marburg Vaccine Shows Promise

JAMA. 2006;295(20):2346. doi:10.1001/jama.295.20.2346

A new vaccine developed by scientists from the United States and Canada can prevent deadly hemorrhagic fever in monkeys after exposure to the Marburg virus, a naturally virulent pathogen that could also be manipulated for use as agents of bioterrorism (Daddario-DiCaprio KM et al. Lancet. 2006;367:1399-1404). Earlier research by the team demonstrated that the vaccine could prevent Marburg hemorrhagic fever from developing when given before infection (Jones SM et al. Nat Med. 2005;11:786-790), but these latest results suggest that the vaccine could also be an effective postexposure treatment.

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