Author Affiliation: Feinberg School of Medicine, Northwestern University, Chicago, Ill.
Brain metastases are the most feared and debilitating complication of systemic cancers. They affect approximately 170 000 patients a year, with the most common primary tumors being lung cancer, breast cancer, and melanoma.1 The traditional approach for patients with brain metastases has been whole-brain radiation therapy (WBRT), irrespective of lesion number or primary site.
Raizer J. Radiosurgery and Whole-Brain Radiation Therapy for Brain MetastasesEither or Both as the Optimal Treatment. JAMA. 2006;295(21):2535-2536. doi:10.1001/jama.295.21.2535