Author Affiliations: Dr DeAngelis is Editor in Chief (email@example.com) and Dr Zuccotti is Contributing Editor, JAMA.
Malaria is an ancient disease, with descriptions of a disease resembling malaria that date back more than 4000 years.1 There have been many advances in malaria research, including the discovery of the malaria parasite in 1880 by Laveran, for which he was awarded the Nobel Prize in 19041; the control of mosquitoes responsible for disease transmission in the early part of the 20th century; the discovery of the antimalarial drug, chloroquine, in 1934 by Andersag; the use of dichlorodiphenyltrichloroethane (DDT) as an insecticidal agent beginning in 1939 that was followed by the use of less toxic insecticides1; and the discovery and use of other antimalarial drugs and drug combinations, including sulfadoxine-pyrimethamine, mefloquine, atovaquone-proguanic, quinine, and doxycycline.2
DeAngelis CD, Zuccotti G. Theme Issue on MalariaA Call for Papers. JAMA. 2006;296(10):1289. doi:10.1001/jama.296.10.1289