In Reply: Our article did not state that there is no evidence of an association between exposure to mercury vapor released from amalgams and human health risks. To paraphrase Paracelsus,1 it is the dose that makes the poison. We reported that, at the levels of amalgam exposure experienced by the children enrolled in the New England Children's Amalgam Trial, we did not observe any adverse effects on neuropsychological or renal function.
McKinlay SA. Risks of Dental Amalgam in Children—Reply. JAMA. 2006;296(12):1461. doi:10.1001/jama.296.12.1461-b