Author Affiliations: Division of Cardiology, Hartford Hospital and University of Connecticut, Hartford (Dr Thompson); Institute for Exercise and Environmental Medicine, Presbyterian Hospital, and University of Texas Southwestern Medical Center, Dallas (Dr Levine).
The cardiovascular benefits of regular physical activity have been well documented,1 but vigorous exercise can also transiently increase the risk of sudden cardiac death.2- 4 Exercise-related sudden death in adults is primarily due to coronary artery disease,2,5 whereas such events in younger individuals are due to a variety of congenital and genetic cardiovascular disorders, including inherited cardiomyopathies and arrhythmias, anomalies of the coronary arteries or to acquired cardiomyopathy.6- 8
Thompson PD, Levine BD. Protecting Athletes From Sudden Cardiac Death. JAMA. 2006;296(13):1648-1650. doi:10.1001/jama.296.13.1648