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Medical News and Perspectives
November 15, 2006

Researchers Probe Consequences of Androgen Deprivation for Prostate Cancer

JAMA. 2006;296(19):2305-2306. doi:10.1001/jama.296.19.2305

Boston—Because prostate cancer growth is fueled by androgens—especially testosterone—androgen deprivation therapy (ADT) is the treatment of choice for the 40% of men with this cancer who have disease that has spread beyond the prostate, a condition not amenable to surgical cure. While ADT achieves temporary symptom relief and tumor control in up to 80% of cases, this comes at a cost, said Laurence Katznelson, MD, associate professor of medicine and neurosurgery at Stanford University School of Medicine, Palo Alto, Calif.

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