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Health Agencies Update
November 22/29, 2006

Macular Degeneration

JAMA. 2006;296(20):2429. doi:10.1001/jama.296.20.2429-c

The National Institutes of Health is launching a new study to see if a combination of vitamins, minerals, and fish oil can slow the progression of vision loss from age-related macular degeneration, the leading cause of vision loss in the United States for individuals older than 60 years. This trial, called the Age-Related Eye Disease Study 2 (AREDS2), will build upon results from the earlier Age-Related Eye Disease Study (AREDS) that 5 years ago found that high-dose antioxidant vitamins and minerals (vitamins C and E, beta-carotene, zinc, and copper) reduced the risk of progression to advanced age-related macular degeneration by 25% and the risk of moderate vision loss by 19% (

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