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December 6, 2006

Morbidity or Mortality Outcomes Associated With Prophylactic Salpingo-oophorectomy

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2006;296(21):2558. doi:10.1001/jama.296.21.2558-a

To the Editor: The study of women with a BRCA1 or BRCA2 mutation by Ms Finch and colleagues1 found that for cancer, the adjusted relative risk reduction associated with bilateral salpingo-oophorectomy was 80% (95% confidence interval, 42%-93%). While this is valuable information for advising women at risk, no mention was made of morbidity or mortality secondary to this surgery.

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