Letters Section Editor: Robert M. Golub, MD, Senior Editor.
To the Editor: The study of women with a BRCA1 or BRCA2 mutation by Ms Finch and colleagues1 found that for cancer, the adjusted relative risk reduction associated with bilateral salpingo-oophorectomy was 80% (95% confidence interval, 42%-93%). While this is valuable information for advising women at risk, no mention was made of morbidity or mortality secondary to this surgery.
McCunniff D. Morbidity or Mortality Outcomes Associated With Prophylactic Salpingo-oophorectomy. JAMA. 2006;296(21):2558. doi:10.1001/jama.296.21.2558-a