Letters Section Editor: Robert M. Golub, MD, Senior Editor.
To the Editor: A growing body of literature focuses on how to handle incidental findings, ranging from unexpected masses visualized in radiological imaging to unanticipated findings in the course of surgery or other treatments. In their Commentary, Dr Kohane and colleagues1 appropriately point to the potential for incidental findings in genome-scale screening. However, they fail to make a critical distinction between incidental findings in human subject research and incidental findings in the course of clinical treatment.
Wolf SM, Kahn JP, Lawrenz FP, Nelson CA. The Incidentalome. JAMA. 2006;296(23):2800-2802. doi:10.1001/jama.296.23.2800-b