Lab, Field, and Clinic
January 3, 2007

Healing Power Found in “Nano Knitting”

JAMA. 2007;297(1):31. doi:10.1001/jama.297.1.31

A novel technology using tiny “nanofibers” shows promise for helping the body repair and restore tissue damaged through injury or disease, including brain trauma, according to new research (Ellis-Behnke RG et al. Proc Natl Acad Sci U S A. 2006;103:5054-5059). The same material applied to a wound may also help surgeons stanch bleeding within seconds.

The nanoscale fibers are composed of peptides that self-assemble into a fibrous mesh that mimics the natural connective tissue of the body's extracellular matrix. “The peptide nanofiber scaffold not only represents a previously undiscovered nanobiomedical technology for tissue repair and restoration but also raises the possibility of effective treatment of [central nervous system] and other tissue or organ trauma,” the researchers noted.

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