Letters Section Editor: Robert M. Golub, MD, Senior Editor.
To the Editor: The I-ELCAP investigators1 reported the results of a cross-sectional analysis of their series of 16 925 healthy smokers who underwent CT screening. This analysis indicated a higher prevalence of screen-detected lung cancers in women than in men. A prospective analysis indicated increased survival in women with lung cancer compared with men who had lung cancer. The authors interpret their findings as evidence that women are more susceptible to the carcinogenic effect of tobacco smoke on the lung.
Boffetta P, Tarone RE, Blot WJ. Survival in Women After Diagnosis of Lung Cancer. JAMA. 2007;297(2):153-154. doi:10.1001/jama.297.2.153-a