Letters Section Editor: Robert M. Golub, MD, Senior Editor.
To the Editor: In their Commentary, Dr Kraemer and colleagues1 raise the important issue of exploring moderators of treatment outcome in randomized trials. I agree that reliance on the P value for hypothesis testing has limited value for clinicians who need to decide if a treatment is appropriate for a particular patient. There are also 2 other points to consider.
Shrier I. A Word From Our Moderator. JAMA. 2007;297(2):156-157. doi:10.1001/jama.297.2.156-b