Letters Section Editor: Robert M. Golub, MD, Senior Editor.
To the Editor: Dr Atik and colleagues1 studied the prevalence of active trachoma and ocular Chlamydia trachomatis infection in 3 Vietnamese communes. Two communes (Surgery for trachomatous trichiasis; Antibiotics for Chlamydia trachomatis infection; [SA], and Surgery for trachomatous trichiasis; Antibiotics for Chlamydia trachomatis infection; Facial cleanliness; Environmental improvement [SAFE])were selected to receive azithromycin using a targeted approach in which schoolchildren aged 5 to 15 years with signs of active trachoma and their household contacts were treated. A third commune that did not receive oral antibiotics served as a control. Because no association was found between clinical signs and the presence of ocular C trachomatis infection, only a small proportion of infected individuals was treated with azithromycin: 4% and 11% of the 2 SA and SAFE communes, respectively, at baseline; and 0% and 10% at 1 year.
Mabey D, Bailey R, Solomon A, Burton M, Gilbert C, Foster A, Lietman T, West S. Targeted Treatment of Active Trachoma. JAMA. 2007;297(6):588-590. doi:10.1001/jama.285.6.734