Letters Section Editor: Robert M. Golub, MD, Senior Editor.
In Reply: Dr Kaufman suggests that the method for skin preparation outlined in our review should be abandoned. Unfortunately, we were unable to find any randomized trials of the effect of sterile technique (including application of antiseptics, use of sterile drapes, or use of sterile gown and gloves) on adverse events. Instead, we had to rely on current standard of practice, which we derived from a survey of 120 medicine residents and discussion with several expert clinicians.
Straus SE, Holroyd-Leduc J. How to Perform a Lumbar Puncture—Reply. JAMA. 2007;297(8):810-811. doi:10.1001/jama.297.8.811