Letters Section Editor: Robert M. Golub, MD, Senior Editor.
In Reply: We agree with Dr Mariotto that many diverse factors contribute to hypertension and success in its management and that the evaluation of such potential confounders is an important step in the evaluation of clinical trials. The intervention used in the Federal Study of Adherence to Medications in the Elderly focused on adherence to medications that have known efficacy in the treatment of hypertension and hyperlipidemia. No data were collected on factors such as physical activity or diet, so we cannot present a comparison between the study groups or adjust for any differences.
Taylor AJ, Lee JK, Grace KA. Pharmacy Care Programs and Clinical Outcomes—Reply. JAMA. 2007;297(16):1771-1772. doi:10.1001/jama.297.16.1772-a