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Lab Reports
May 2, 2007

Glucocorticoids and Newborns

JAMA. 2007;297(17):1870. doi:10.1001/jama.297.17.1870-d

Prenatal exposure of nonhuman primates to glucocorticoids has long-lasting deleterious effects on cardiovascular, metabolic, and neuroendocrine function, according to a recent study by investigators at the University of Edinburgh, in Scotland (de Vries A et al. J Clin Invest. doi:10.1172/JCI30982 [published online March 22, 2007]). The effect has been documented in rodents and other nonprimates, and now the findings are mirrored in African vervet monkeys (Chloroceus aethiops).

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