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Book and Media Reviews
May 16, 2007


Author Affiliations

Book and Media Reviews Section Editor: John L. Zeller, MD, PhD, Fishbein Fellow.

JAMA. 2007;297(19):2141-2144. doi:10.1001/jama.297.19.2141-b

Myocardial infarction and sudden cardiac death, 2 of the so-called acute coronary syndromes, are the most common causes of death in the world. Together with stroke and peripheral vascular disease, these syndromes constitute the major atherothrombotic diseases of cardiovascular medicine. Platelets play a central role in the pathophysiology of these syndromes, and therapeutic alteration of platelet function is a cornerstone of their treatment. Platelets also play a key role in inflammation, hemorrhagic diseases, and cancer. So, the study of platelets is of interest to a number of specialties, including hematology but also cardiology, neurology, pathology, and others. Getting one's arms around the mass of accumulating information about platelets and organizing it is a difficult task and, indeed, a moving target. This organizational role is specifically addressed by Alan Michelson's second edition of his textbook Platelets.

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