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May 16, 2007

Low- vs High-Dose Estradiol Vaginal Ring in Treatment of Sexual Difficulties

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2007;297(19):2076-2077. doi:10.1001/jama.297.19.2076-b

To the Editor: The Clinical Crossroads article by Dr Potter1 discussed the use of vaginal estrogen therapy for a 60-year-old woman with sexual difficulties. The article stated that the patient “switched to an estradiol vaginal ring because of its ease of use,” but doesn't note the content of the device. The article later states that “ . . . both tablets and ring relieve atrophy with minimal systemic absorption . . . the addition of progestin to prevent endometrial hyperplasia is generally not advocated . . . ”

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