Letters Section Editor: Robert M. Golub, MD, Senior Editor.
To the Editor: Dr Halonen and colleagues1 found that intravenous hydrocortisone significantly reduced the incidence of AF after cardiac surgery with cardiopulmonary bypass (adjusted hazard ratio, 0.54; 95% confidence interval, 0.35-0.83; P = .004; number needed to treat, 5.6). The statistical analysis accounted for established predictors of AF, such as age, sex, ejection fraction, type of operation, pulmonary disease, and coronary artery disease.
Augoustides JGT. Use of Corticosteroids to Prevent Atrial Fibrillation After Cardiac Surgery. JAMA. 2007;298(3):283-284. doi:10.1001/jama.298.3.283-b