[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 241
Citations 0
Health Agencies Update
December NaN, 2014

Unique Mice May Help Reveal Human Response to Chemical Exposure

JAMA. 2014;312(24):2608. doi:10.1001/jama.2014.17033

New research conducted in part by scientists at the National Institutes of Health suggests that a genetically diverse mouse model, referred to as “Diversity Outbred” mice, will help predict the range of biological responses that may occur within a population after different chemical exposures (French JE et al. Environ Health Perspect.doi:10.1289/ehp.1408202 [published online November 6, 2014]). Traditionally, isogenic mice are used to assess the effects of exposure; however, because of lack of genetic diversity, these models may not accurately predict the range of sensitivities to chemicals in humans.

First Page Preview View Large
First page PDF preview
First page PDF preview