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Comment & Response
December NaN, 2014

Energy Intake and Weight Loss

Author Affiliations
  • 1Nutrition Obesity Research Center, University of Alabama, Birmingham
  • 2Center for Quantitative Obesity Research, Montclair State University, Montclair, New Jersey
  • 3Pennington Biomedical Research Center, Baton Rouge, Louisiana
JAMA. 2014;312(24):2687-2688. doi:10.1001/jama.2014.15513

To the Editor In a recent JAMA Patient Page, Dr Guth1 stated that “A total of 3500 calories equals 1 pound of body weight.” However, the energy content of body weight varies widely by race, sex, and age. The calorie density value of 3500 is based on the composition of adipose tissue. However, humans are rarely more than half adipose tissue; most of the remainder is skeletal muscle and bone, which have much lower calorie densities.

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