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August 22/29, 2007

Off-Label Use of Drug-Eluting Stents—Reply

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2007;298(8):859-860. doi:10.1001/jama.298.8.859-b

In Reply: In response to Dr Bobba and colleagues, of the 6993 patients in the D.E.S.cover registry who received drug-eluting stents, 1009 (14.4%) had stable angina as the indication for PCI. In our analysis of 5541 patients who received drug-eluting stents only and could be classified by type of use, 5515 had complete data on medical therapy at discharge (Table). These data indicate in real-world clinical practice relatively aggressive but not uniform post-PCI medical therapy that does not vary appreciably by off-label vs standard use of drug-eluting stents.

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