To the Editor The Special Communication reporting a summary of the National Heart, Lung, and Blood Institute expert panel report on the management of patients with sickle cell disease (SCD)1 distilled best practice recommendations from the extensive sickle cell anemia literature. However, the recommendation that chelation therapy should be standard for patients with SCD and iron overload failed to consider an important aspect of the problem.
Pollack S. Management of Patients With Sickle Cell Disease. JAMA. 2015;313(1):90-91. doi:10.1001/jama.2014.15895