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Comment & Response
January 6, 2015

Management of Patients With Sickle Cell Disease

Author Affiliations
  • 1Pulmonary Center, Boston University School of Medicine, Boston, Massachusetts
  • 2Division of Hematology and Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania
  • 3Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
JAMA. 2015;313(1):91. doi:10.1001/jama.2014.15898

To the Editor As members of the guideline committee sponsored by the American Thoracic Society on the diagnosis and treatment of pulmonary hypertension in patients with SCD,1 we would like to emphasize several important differences between our guidelines and the pulmonary hypertension recommendations made by Dr Yawn and colleagues.2 We concur that an echocardiogram is an essential part of the evaluation of patients with SCD and unexplained dyspnea and that right heart catheterization is required for diagnosis of pulmonary hypertension.

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