[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.92.62. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 553
Citations 0
Comment & Response
January 6, 2015

Reanalyses of Trial Results—Reply

Author Affiliations
  • 1Meta-Research Innovation Center at Stanford, Stanford University, Stanford, California
JAMA. 2015;313(1):93. doi:10.1001/jama.2014.15644

In Reply Drs Platts-Mills and Jones have raised a potential concern with the search strategy used in our study on reanalyses of randomized clinical trial data, specifically with respect to our restriction to studies indexed as a clinical trial publication type in MEDLINE. We agree with them that a strategy with no restriction to clinical trials publication type would be more sensitive in detecting reanalyses.

However, performing such a search would yield a total of 112 330 citations (limited to March 9, 2014, as per our original search). Screening this number of citations would be a daunting task and may not be a valuable use of resources if the output of additional studies retrieved would be few in number compared with the studies retrieved in our original search.

First Page Preview View Large
First page PDF preview
First page PDF preview
×