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From the JAMA Network
January 27, 2015

Nonleg Venous Thrombosis in Critically Ill Adults

Author Affiliations
  • 1University of Ottawa, Ottawa, Ontario, Canada
  • 2Department of Medicine, Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada
JAMA. 2015;313(4):411-412. doi:10.1001/jama.2014.12496

Venous thromboembolism (VTE) comprises deep vein thrombosis (DVT) of the lower extremity and pulmonary embolism (PE) and is the third most common cardiovascular disease after acute myocardial infarction and stroke, affecting up to 5% of the population during their lifetime.1 The epidemiology of thrombosis at other sites, including upper extremity veins, intra-abdominal veins, and cerebral veins, is less well defined, and the reported frequency depends on the data source.2 The optimal treatment for nonleg deep vein thrombosis (NLDVT) is unclear because there are no prospective management studies and current recommendations are based on expert opinion and extrapolation from proximal leg DVT studies.

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