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Lab Reports
November 7, 2007

Liver Failure Treatment

JAMA. 2007;298(17):1998. doi:10.1001/jama.298.17.1998-c

Manipulating the body's immune response may be an effective way to treat liver failure, according to animal studies by researchers at the Massachusetts General Hospital, in Boston (Parekkadan B et al. PLoS ONE. doi: 10.1371/journal.pone.0000941 [published online September 26, 2007]). Specifically, the administration of molecules secreted from multipotent bone marrow–derived mesenchymal stem cells can provide a significant survival benefit in rats undergoing hepatic failure. Computed tomography revealed that the treatment diverts immune cells from the injured organ.

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