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November 21, 2007

High-Density Lipoprotein and Dietary Fatty Acids

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2007;298(19):2263-2264. doi:10.1001/jama.298.19.2263-c

To the Editor: In the systematic review of high-density lipoprotein as a therapeutic target by Dr Singh and colleagues,1 the authors summarized nonpharmacological interventions to increase levels of high-density lipoprotein cholesterol (HDL-C). When discussing interventions involving dietary factors, they stated that “Diets rich in saturated fatty acids and trans-fatty acids can increase HDL-C levels. . . . ” However, this statement is not entirely consistent with the effect of individual dietary fatty acids on serum lipids.

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