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Letters
November 28, 2007

Diabetes and Mortality Risk After Acute Coronary Syndromes

JAMA. 2007;298(20):2367-2368. doi:10.1001/jama.298.20.2367-a

To the Editor: In their study of diabetes and mortality following acute coronary syndromes (ACS), Dr Donahoe and colleagues1 reported higher mortality in patients at 30 days and 1 year after ACS by performing subgroup analysis on pooled data from 11 independent Thrombolysis in Myocardial Infarction (TIMI) trials. The authors state that mortality remains high despite available modern evidence-based treatment. However, the data presented show that proven and available measures for secondary prevention remain underused. Adverse clinical outcomes and underuse of secondary prevention strategies have been reported to be associated with worse clinical outcomes in patients with diabetes presenting with ACS.2,3

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