Medical News and Perspectives
December 5, 2007

New Therapies for Alcohol Dependence Open Options for Office-Based Treatment

JAMA. 2007;298(21):2467-2468. doi:10.1001/jama.298.21.2467

As evidence grows to support the combined use of medication and psychosocial intervention to help individuals with alcohol dependence, treatment of alcohol use disorders is increasingly shifting to the primary care office setting.

The US Food and Drug Administration (FDA) has approved 3 medications for the treatment of alcohol dependence: disulfiram, acamprosate, and naltrexone (the latter in both daily oral and monthly injectable formulations). The availability of these drugs, along with mounting evidence of their effectiveness when coupled with brief behavioral interventions, is making office-based care more feasible.

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