Madrid, Spain—Often a final and fatal step in cancer progression, metastasis causes 90% of all cancer deaths and is associated with a median survival after diagnosis of less than 2 years. But ongoing research efforts are providing clues to potential therapeutic targets by deciphering the complex genetic events that enable tumor cells to disseminate and invade distant organs.
Scientists discussed some of the latest findings at Oncogenes and Human Cancer: The Next 25 Years, a recent conference celebrating the 25th anniversary of the isolation of oncogenes from human tumors.
Hampton T. Researchers Deconstruct Metastasis. JAMA. 2007;298(21):2471. doi:10.1001/jama.298.21.2471