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The World in Medicine
December 19, 2007

HIV Vaccine Concerns?

JAMA. 2007;298(23):2733. doi:10.1001/jama.298.23.2733-b

An experimental HIV vaccine used in an international trial may have increased the risk of HIV infection among vaccine recipients, according to reports in November at a special open meeting of the HIV Vaccine Trials Network in Seattle ( The phase 2 trial, which involved 3000 volunteers at high risk for HIV infection, was halted in late September after a preliminary analysis revealed the vaccine had failed to show efficacy.

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