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JAMA Clinical Challenge
February 3, 2015

Skin and Mouth Lesions Plus Weight Loss in an Elderly Man

Author Affiliations
  • 1Dermatology Clinical Research, Center for Clinical Studies, Houston, Texas
  • 2Department of Dermatology, University of Texas Health Science Center at Houston
JAMA. 2015;313(5):514-515. doi:10.1001/jama.2014.17010

A 74-year-old white man of British descent with a medical history of atrial fibrillation treated with warfarin presented to a dermatology clinic with multiple dark skin lesions on his neck, chest, abdomen, and upper extremities, as well as dark red lesions in his mouth of 4 months’ duration. During this period, he had been seen by his primary care physician as well as by hematology, dermatology, and cardiology specialists, who had told the patient his lesions were ecchymoses secondary to warfarin anticoagulation.

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