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Comment & Response
February 3, 2015

Age Cutoffs for Bioprosthetic vs Mechanical Aortic Valve Replacement

Author Affiliations
  • 1Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands

Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2015;313(5):522-523. doi:10.1001/jama.2014.17228

To the Editor Mr Chiang and colleagues1 reported that patients aged 50 to 69 years who underwent aortic valve replacement had comparable 15-year survival with implantation of a bioprosthesis or a mechanical prosthesis, suggesting that bioprosthetic valves “may be a reasonable choice” in patients aged 50 years or older. We recognize that, in part because of the advent of transcatheter aortic valve implantation and the possibility of placing a transcatheter heart valve in bioprosthetic valves with structural valve deterioration,2 bioprostheses are becoming a more attractive alternative to mechanical prostheses.3 However, additional data are required before lowering the age cutoff for implanting bioprostheses can be justified.

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