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Letters
July 12, 2006

Endogenous Sex Hormones and Type 2 Diabetes Risk

Author Affiliations
 

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2006;296(2):168-170. doi:10.1001/jama.296.2.169-a

To the Editor: Dr Ding and colleagues1 concluded that there are sex-specific etiologies of type 2 diabetes because diabetes mellitus is associated with relatively elevated testosterone levels in women while the reverse holds true for men. An alternate explanation is that visceral adiposity could be a primary factor that contributes to the development of insulin resistance, altered sex steroid and sex hormone–binding globulin (SHBG) production, and diabetes in both sexes.

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