[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
July 19, 2006

Low-Fat Diet and Cardiovascular Disease

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2006;296(3):279-281. doi:10.1001/jama.296.3.280-a

To the Editor: Concerns about the validity of observational data provided justification for the WHI randomized clinical trials (RCTs). Results from several of these trials, including the one by Dr Howard and colleagues,1 have now been published and are being interpreted as providing evidence that dietary modification,1 hormone therapy,2 and calcium/vitamin D3 are not efficacious. This conclusion is premature and results in part from failure to consider the limitations of RCTs.

First Page Preview View Large
First page PDF preview
First page PDF preview