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Book and Media Reviews
July 26, 2006

Pediatric Oncology

Author Affiliations

Book and Media Reviews Section Editor: Harriet S. Meyer, MD, Contributing Editor, JAMA.

JAMA. 2006;296(4):450-455. doi:10.1001/jama.296.4.452-b

Few areas in medicine can match the remarkable progress achieved in the practice of pediatric oncology during the latter half of the 20th century—from a field in which few patients survived long after their cancer diagnosis to one in which the majority of patients can look forward to a cure. This progress is the result of a broad range of medical advances, such as the introduction of combination chemotherapy, dose-intensive therapy, cooperative group clinical treatment trials, multidisciplinary medical/surgical care, psychosocial support, hematopoietic stem cell transplantation, and immunotherapy. Now, in the early years of the 21st century, we are witnessing explosive growth in the fields of molecular biology and genetics. This growth has led to remarkable insights, not only into the fundamental chemical processes of life but also into the molecular events that define cancer, and has led to the implementation of novel therapeutic concepts poised to sustain treatment advances for the foreseeable future.

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