March 17, 2015

Beyond Myalgic Encephalomyelitis/Chronic Fatigue SyndromeAn IOM Report on Redefining an Illness

Author Affiliations
  • 1Center for Biomedical Ethics and Society, Vanderbilt University, Nashville, Tennessee

Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2015;313(11):1101-1102. doi:10.1001/jama.2015.1346

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystem and often long-lasting disorder, with manifestations that can cause substantial morbidity and can severely impair patients’ health and well-being. It is estimated that between 836 000 and 2.5 million individuals are affected in the United States.1,2 Patients with ME/CFS are typically unable to perform their normal activities, and as many as one-fourth are homebound or bedridden, sometimes for extended periods.3 As a result, the personal and social effects and ramifications of this disease are enormous.

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