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July 23, 1910


Author Affiliations


From the Laboratory of Pathology of the University of Louisville.

JAMA. 1910;55(4):312-313. doi:10.1001/jama.1910.04330040048017

For many years papers have appeared intermittently recommending the use of oil in the peritoneal cavity to prevent the formation of alhesions.

When we began our work in the laboratory on this subject we could find no paper dealing with it from an experimental standpoint; though while this work was in progress the paper by Wilkie1 appeared. He formed adhesions in twelve animals (cats) by irritating the peritoneum. At the end of six or eight weeks these adhesions were broken down and in six of the animals a liquid paraffin was smeared over the raw surfaces. At the end of a month the animals treated with the paraffin showed fewer and less dense adhesions than the controls. The oil was not found free in the peritoneal cavity after fifteen days in macroscopic quantities.

In the work performed by us we have used dogs entirely and have compared the value

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